The occurrence of side effects is a major global health problem, particularly affecting older adults. Identifying the magnitude and predictors of adverse events is critical to developing strategies to reduce the burden of adverse events.Prevalence, characteristics, and risk factor prediction of adverse events in hospitalized older adults: a systematic review and meta-analysis

Prevalence, characteristics, and risk factor prediction of adverse events in hospitalized older adults: a systematic review and meta-analysis

Descriptive statistics and mean comparisons were performed using SPSS version 20.0 and metaprop assignment was performed in STATA version 13.0. Heterogeneity was assessed using the I2 statistic.

Results:
A total of 18 studies were included in this study, involving 80,695 participants with an average age of 77 years. The pooled prevalence of adverse events was 22% (95% confidence interval: 17%, 28%; I2 = 99.23%). In high-income countries, the incidence of adverse events was 29% (95% confidence interval: 16%, 42%),

Compared with 19% (95% confidence interval: 14%-25%) in low- and middle-income countries. countries (p-value = 0.176). Of the 620 adverse events categorized, most were type A (89%),

which are generally predictable and preventable. Two-thirds (795, 67%) of adverse events were probable and most (1,194, 69%) were mild or moderate. The majority (60%) of categorized adverse events were preventable and less than a third (31%) were serious.

risk factor prediction of adverse events in hospitalized

The most commonly reported predictors of adverse events in hospitalized elderly patients were drug-related factors, including polypharmacy and potentially inappropriate medication, followed by disease-related factors: renal failure, complex comorbidities, heart failure, and liver failure.

Diploma:
Nearly a quarter of all hospitalized older adults experienced at least one adverse event during their hospital stay. Most side effects were preventable. Drug-related factors were the most commonly reported predictors of adverse events, followed by disease-related factors.risk factor prediction of adverse events in hospitalized

Keywords: prevalence, adverse effects, predictors, hospitalization, older adults
Go to:
According to the World Health Organization (WHO)1, an adverse drug reaction is defined as “any harmful and unintended reaction to a drug .

Occurring at doses normally used in humans for the prophylaxis, diagnosis or treatment of disease or the alteration of physiological Function.”

The occurrence of adverse events represents a major patient safety problem worldwide and affects different age groups. The elderly population aged 60 and over is most at risk. Adverse events contribute significantly to morbidity and mortality worldwide.risk factor prediction of adverse events in hospitalized

2–4 Among older hospitalized patients, a significant proportion (15–35%) experience an adverse event during their hospital stay

.5–7 Approximately 10% of hospital admissions are associated with an adverse event. 8–10 In the United States, approximately 100,000 acute hospitalizations of older adults each year have been attributed to adverse events. 11 Most adverse events in older adults are predictable and preventable and are caused by commonly prescribed medications.12 More serious adverse events occur more frequently. probably avoidable.13

WHO14 defines older adults (elderly people) as people aged 60 years and over.

admin

Leave a Reply

Your email address will not be published. Required fields are marked *